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B) What are the limiting factors in your study that may affect the possibility of generalizing your results? A brief description of any solutions to the problem that have been tried in the past should be given, how well they have worked, and why further research is needed. This study is ongoing to evaluate the administration of andexanet alfa bolus plus extended-duration infusion. Are there confounding variables that might affect the cause-effect relationship? the sampling or selection method/criteria, and justification of sample size (power calculation). Ethical considerations: State how you intend to follow the ethical rules (e.g. This article is published on November 8, 2011. Work plan and budget, this section should cover issues like task allocation, organization of venues, transport etc., as well as a time schedule (including all aspects of the study).

NEW Check my paper, citing and more! Preclinical and Phase 1 studies suggest that andexanet alfa has the potential to be a universal reversal agent for all Factor Xa inhibitors. You are here: Home articles methods format for a quantitative research proposal. If it is an observational study, is it a descriptive study or an analytical study (cross-sectional, case-control, cohort study). A, table of Contents (including headings and page numbers) and. In the case of an intervention study, describe the interventions that the treatment and control groups receive. I only want to create citations. These randomized, double-blind, placebo-controlled studies are designed to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of andexanet alfa after dosing of a direct/indirect Factor Xa inhibitor in healthy volunteers.